Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Brugada Syndrome Whose ST-segment Changes were Enhanced by Antihistamines and Antiallergenic Drugs
Motoki Matsuki, Nobuyuki Sato, Kanako Matsuda, Masaru Yamaki, Naoki Nakagawa, Naka Sakamoto, Hisanobu Ota, Yasuko Tanabe, Toshiharu Takeuchi, Kazumi Akasaka, Yuichiro Kawamura, Naoyuki Hasebe
著者情報
キーワード: Brugada syndrome, antihistamines, antiallergenic drugs
ジャーナル オープンアクセス

2009 年 48 巻 12 号 p. 1009-1013

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We describe a case of Brugada syndrome, in which a coved type ST-segment elevation was enhanced by antihistamines and antiallergenic drugs. The patient had been treated with four kinds of antihistamines and antiallergenic drugs. The twelve-lead ECG exhibited a coved type ST-segment elevation in leads V1 and V2, and their enhancement was induced by pilsicainide. After discontinuing those drugs, the ST segment elevation in leads V1 and V2 became reduced. An ICD implantation was selected for the therapy since ventricular fibrillation was induced. Our report discusses the possible contribution of antihistamines and antiallergenic drugs to the Brugada type ST-segment changes.

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© 2009 by The Japanese Society of Internal Medicine
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Japanese Journal of Medicine

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