Massive Eosinophilic Pleural Effusion Preceding Vasculitic Symptoms in Churg-Strauss Syndrome

Kiminobu Tanizawa; Yusuke Kaji; Eisaku Tanaka; Tetsuro Inoue; Minoru Sakuramoto; Masayoshi Minakuchi; Yuji Maeda; Ko Maniwa; Kunihiko Terada; Shunsuke Goto; Tomoshi Takeda; Masaki Okamoto; Seishu Hashimoto; Satoshi Noma; Yoichiro Kobashi; Yoshio Taguchi

doi:10.2169/internalmedicine.49.2839

CASE REPORTS

Massive Eosinophilic Pleural Effusion Preceding Vasculitic Symptoms in Churg-Strauss Syndrome

Kiminobu Tanizawa, Yusuke Kaji, Eisaku Tanaka, Tetsuro Inoue, Minoru Sakuramoto, Masayoshi Minakuchi, Yuji Maeda, Ko Maniwa, Kunihiko Terada, Shunsuke Goto, Tomoshi Takeda, Masaki Okamoto, Seishu Hashimoto, Satoshi Noma, Yoichiro Kobashi, Yoshio Taguchi

著者情報

キーワード: Churg-Strauss syndrome, eosinophilic pleural effusion, bronchial asthma

ジャーナルオープンアクセス

2010 年 49 巻 9 号 p. 841-845

DOI https://doi.org/10.2169/internalmedicine.49.2839

詳細

抄録

We report a case of Churg-Strauss syndrome (CSS) presenting as a massive pleural effusion. A 52-year-old asthmatic Japanese woman presented with progressive dyspnea caused by an eosinophilic pleural effusion (EPE). She also had chronic sinusitis, skin lesions and blood eosinophilia, but no antineutrophil cytoplasmic antibodies. Skin biopsy and the late onset of mononeuritis multiplex led to the diagnosis of CSS. The pleural effusion resolved soon after corticosteroid treatment was started. CSS is rare as a cause of EPE, but should be included in the differential diagnosis of EPE in asthmatic patients. This is the first report showing that EPE can precede other vasculitic symptoms in CSS.

責任著者(Corresponding author)

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