Upper Gastrointestinal Sarcoidosis: Report of Three Cases

Minoru Inomata; Soichiro Ikushima; Nobuyasu Awano; Keisuke Kondoh; Kohta Satake; Masahiro Masuo; Atsuko Moriya; Hiroyuki Kamiya; Tsunehiro Ando; Arata Azuma; Tamiko Takemura

doi:10.2169/internalmedicine.51.7367

CASE REPORTS

Upper Gastrointestinal Sarcoidosis: Report of Three Cases

Minoru Inomata, Soichiro Ikushima, Nobuyasu Awano, Keisuke Kondoh, Kohta Satake, Masahiro Masuo, Atsuko Moriya, Hiroyuki Kamiya, Tsunehiro Ando, Arata Azuma, Tamiko Takemura

著者情報

Minoru Inomata
Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Division of Pulmonary Medicine, Infectious Diseases, and Oncology Department of Internal Medicine, Nippon Medical School, Japan
Soichiro Ikushima
Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Nobuyasu Awano
Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Keisuke Kondoh
Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Kohta Satake
Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Masahiro Masuo
Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Atsuko Moriya
Department of Infectious Disease, Japanese Red Cross Medical Center, Japan
Hiroyuki Kamiya
Department of Respiratory Medicine, Japanese Red Cross Medical Center, Japan
Tsunehiro Ando
Department of Infectious Disease, Japanese Red Cross Medical Center, Japan
Arata Azuma
Division of Pulmonary Medicine, Infectious Diseases, and Oncology Department of Internal Medicine, Nippon Medical School, Japan
Tamiko Takemura
Department of Pathology, Japanese Red Cross Medical Center, Japan

キーワード: gastric sarcoidosis, duodenal sarcoidosis, noncaseating epithelioid cell granuloma, upper endoscopy, glucocorticoid therapy, proton pump inhibitor

ジャーナルオープンアクセス

2012 年 51 巻 13 号 p. 1689-1694

DOI https://doi.org/10.2169/internalmedicine.51.7367

詳細

抄録

Involvement of the upper gastrointestinal tract in sarcoidosis is rare, and an optimal treatment regimen remains to be determined. Here, we report 3 cases of upper gastrointestinal sarcoidosis in Japanese patients aged 57-70 years with or without epigastric symptoms and describe the clinical features, laboratory data, and upper endoscopy and pathological findings. Upper gastrointestinal sarcoidosis was diagnosed based on the presence of noncaseating epithelioid cell granuloma in the lamina propria in the stomach or duodenum. In conclusion, the possibility of upper gastrointestinal sarcoidosis should be considered in patients with epigastric symptoms and a history of sarcoidosis, even in those with stable disease.

責任著者(Corresponding author)

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