Toxic Megacolon Associated with Cytomegalovirus Infection in a Patient with Steroid-naïve Ulcerative Colitis

Ken Inoue; Naoki Wakabayashi; Kohei Fukumoto; Shinya Yamada; Nobukatsu Bito; Naohisa Yoshida; Kazuhiro Katada; Kazuhiko Uchiyama; Takeshi Ishikawa; Osamu Handa; Tomohisa Takagi; Hideyuki Konishi; Nobuaki Yagi; Satoshi Kokura; Mitsuo Kishimoto; Akio Yanagisawa; Yuji Naito

doi:10.2169/internalmedicine.51.8145

CASE REPORTS

Toxic Megacolon Associated with Cytomegalovirus Infection in a Patient with Steroid-naïve Ulcerative Colitis

Ken Inoue, Naoki Wakabayashi, Kohei Fukumoto, Shinya Yamada, Nobukatsu Bito, Naohisa Yoshida, Kazuhiro Katada, Kazuhiko Uchiyama, Takeshi Ishikawa, Osamu Handa, Tomohisa Takagi, Hideyuki Konishi, Nobuaki Yagi, Satoshi Kokura, Mitsuo Kishimoto, Akio Yanagisawa, Yuji Naito

著者情報

Ken Inoue
Department of Gastroenterology and Hepatology, Kyoto Prefectural Yosanoumi Hospital, Japan
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Naoki Wakabayashi
Department of Gastroenterology and Hepatology, Otsu Municipal Hospital, Japan
Kohei Fukumoto
Center for Digestive and Liver Disease, Nara City Hospital, Japan
Shinya Yamada
Department of Gastroenterology and Hepatology, Maizuru Medical Center, Japan
Nobukatsu Bito
Department of Gastroenterology and Hepatology, Uji Takeda Hospital, Japan
Naohisa Yoshida
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Kazuhiro Katada
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Kazuhiko Uchiyama
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Takeshi Ishikawa
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Osamu Handa
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Tomohisa Takagi
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Hideyuki Konishi
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Nobuaki Yagi
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Satoshi Kokura
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Mitsuo Kishimoto
Department of Surgical Pathology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Akio Yanagisawa
Department of Surgical Pathology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan
Yuji Naito
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan

キーワード: toxic megacolon, cytomegalovirus, steroid-naïve, ulcerative colitis

ジャーナルオープンアクセス

2012 年 51 巻 19 号 p. 2739-2743

DOI https://doi.org/10.2169/internalmedicine.51.8145

詳細

抄録

Most cases of cytomegalovirus (CMV) colitis in patients with inflammatory bowel disease (IBD) occur in those treated with immunosuppressants and/or corticosteroids. We herein present the case of a 57-year-old man with toxic megacolon associated with CMV colitis in corticosteroid-naïve ulcerative colitis (UC). To date, there have been only eight previous case reports of CMV colitis in steroid-naïve UC. We discuss the need to consider CMV colitis when making a differential diagnosis of patients with refractory UC who are not receiving corticosteroid treatment.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）