Lung Nocardia elegans Infection Diagnosed on Matrix-assisted Laser Desorption Ionization-time of Flight Mass Spectrometry (MALDI-TOF MS)

Yukimasa Ooi; Hideyuki Shiba; Koji Nagai; Tomohiro Higashiyama; Toyofumi Nakanishi; Takashi Nakano; Akira Ukimura; Tohru Gonoi

doi:10.2169/internalmedicine.53.2387

CASE REPORTS

Lung Nocardia elegans Infection Diagnosed on Matrix-assisted Laser Desorption Ionization-time of Flight Mass Spectrometry (MALDI-TOF MS)

Yukimasa Ooi, Hideyuki Shiba, Koji Nagai, Tomohiro Higashiyama, Toyofumi Nakanishi, Takashi Nakano, Akira Ukimura, Tohru Gonoi

著者情報

キーワード: Nocardia elegans, Still's disease, Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS)

ジャーナルオープンアクセス

2014 年 53 巻 18 号 p. 2111-2113

DOI https://doi.org/10.2169/internalmedicine.53.2387

詳細

抄録

A 73-year-old man with adultonset Still's disease developed a high fever, coughing, dyspnea and bloody sputum and was therefore admitted to our hospital. Thoracic X-ray and CT scans revealed oval lesions in the bilateral lungs. A bacterial isolate from the sputum was identified to be Nocardia elegans (N. elegans) on comparative 16S rRNA gene sequencing and Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS). The patient recovered following treatment with imipenem/cilastatin and amikacin. To the best of our knowledge, this is the first case of nocardiosis caused by N. elegans identified on MALDI-TOF MS.

責任著者(Corresponding author)

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