Lacosamide Intoxication-induced Wide QRS Tachycardia Successfully Treated with Veno-arterial Extracorporeal Membrane Oxygenation

Chihiro Takai; Kayo Misumi; Daiki Kaito; Hiroaki Nishida; Masami Yoshii; So Yamada; Takaomi Kobayashi; Toshitaka Koinuma; Takashi Kadoya; Takuya Kimura; Yoshihiro Hagiwara; Takayuki Ogura

doi:10.2169/internalmedicine.0145-22

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Lacosamide Intoxication-induced Wide QRS Tachycardia Successfully Treated with Veno-arterial Extracorporeal Membrane Oxygenation

Chihiro Takai, Kayo Misumi, Daiki Kaito, Hiroaki Nishida, Masami Yoshii, So Yamada, Takaomi Kobayashi, Toshitaka Koinuma, Takashi Kadoya, Takuya Kimura, Yoshihiro Hagiwara, Takayuki Ogura

著者情報

キーワード: lacosamide, antiepileptic, wide QRS tachycardia, electrical storm, ECMO

ジャーナルオープンアクセス早期公開

論文ID: 0145-22

DOI https://doi.org/10.2169/internalmedicine.0145-22

この記事には本公開記事があります。

The final version of this article is now available: Vol. 62 (2023), No. 8 pp. 1185-1189

詳細

抄録

Lacosamide is an antiepileptic drug that acts on voltage-gated sodium channels and was approved as an antiepileptic by the Food and Drug Administration in 2008. Although the efficacy and safety of lacosamide have been established in many previous trials, some case reports have shown that it may lead to cardiovascular side effects, especially in patients with electrical conduction system disorders. We herein report a case of life-threatening cardiac arrhythmia caused by lacosamide intoxication that was successfully treated with veno-arterial extracorporeal membrane oxygenation.

責任著者(Corresponding author)

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