Rapidly Progressive Multiple Cavity Formation in Necrotizing Pneumonia Caused by Community-Acquired Methicillin-resistant Staphylococcus aureus Positive for the Panton-Valentine Leucocidin Gene: A Case Report

Yuki Takigawa; Keiichi Fujiwara; Takashi Saito; Takamasa Nakasuka; Taichi Ozeki; Sachi Okawa; Kenji Takada; Yoshitaka Iwamoto; Hiroe Kayatani; Daisuke Minami; Ken Sato; Miki Nagao; Takuo Shibayama

doi:10.2169/internalmedicine.1454-18

この記事には本公開記事があります。本公開記事を参照してください。
引用する場合も本公開記事を引用してください。

Rapidly Progressive Multiple Cavity Formation in Necrotizing Pneumonia Caused by Community-Acquired Methicillin-resistant Staphylococcus aureus Positive for the Panton-Valentine Leucocidin Gene: A Case Report

Yuki Takigawa, Keiichi Fujiwara, Takashi Saito, Takamasa Nakasuka, Taichi Ozeki, Sachi Okawa, Kenji Takada, Yoshitaka Iwamoto, Hiroe Kayatani, Daisuke Minami, Ken Sato, Miki Nagao, Takuo Shibayama

著者情報

Yuki Takigawa
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Keiichi Fujiwara
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Takashi Saito
Department of Infectious Diseases, National Hospital Organization Okayama Medical Center, Japan
Takamasa Nakasuka
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Taichi Ozeki
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Sachi Okawa
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Kenji Takada
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Yoshitaka Iwamoto
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Hiroe Kayatani
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Daisuke Minami
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Ken Sato
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan
Miki Nagao
Department of Clinical Laboratory, Kyoto University Hospital, Japan
Takuo Shibayama
Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, Japan

キーワード: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), Panton-Valentine leukocidine (PVL) Gene, Necrotizing Pneumonia, Multiple Cavity Formation, Influenza

ジャーナルオープンアクセス早期公開

論文ID: 1454-18

DOI https://doi.org/10.2169/internalmedicine.1454-18

この記事には本公開記事があります。

The final version of this article is now available: Vol. 58 (2019), No. 5 pp. 685-691

詳細

抄録

A 66-year-old man was transferred to our hospital for pneumonia that was resistant to sulbactam/ampicillin and levofloxacin therapy. Chest computed tomography showed the rapidly progressive formation of multiple cavities. Methicillin-resistant Staphylococcus aureus (MRSA) was isolated, and the patient was diagnosed with necrotizing pneumonia caused by community-acquired MRSA (CA-MRSA). The MRSA strain had type IV staphylococcus cassette chromosome mec and genes encoding Panton-Valentine leucocidin (PVL). CA-MRSA necrotizing pneumonia with the PVL gene is rare; only three cases have been previously reported in Japan. We administered anti-MRSA antibiotics and the patient achieved complete clinical and radiological improvement.

責任著者(Corresponding author)

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