Paraneoplastic Cerebellar Degeneration Leading to an Early Diagnosis of Peritoneal Serous Papillary Carcinoma

Tsutomu Yasuda; Jun Shimizu; Toji Miyagawa; Yuri Tsutsumi; Takeshi Iwatsubo; Shoji Tsuji

doi:10.2169/internalmedicine.2894-23

Tsutomu Yasuda, Jun Shimizu, Toji Miyagawa, Yuri Tsutsumi, Takeshi Iwatsubo, Shoji Tsuji

著者情報

キーワード: anti-Yo antibody, paraneoplastic cerebellar degeneration, paraneoplastic neurological syndrome, peritoneal serous papillary carcinoma, neck tremor, ataxia

ジャーナルオープンアクセス早期公開

論文ID: 2894-23

DOI https://doi.org/10.2169/internalmedicine.2894-23

詳細

抄録

A 77-year-old female with a subacute progression of ataxia and serum anti-Yo antibodies was suspected to have paraneoplastic cerebellar degeneration (PCD). An examination of an underlying cancer showed no abnormality in the gynecological organs, but the findings did show a mass in the Douglas fossa. The mass was resected and diagnosed as stage IIB peritoneal serous papillary carcinoma (PSPC), a rare gynecologic cancer that is difficult to diagnose in the early stages. PCD was treated with intravenous immunoglobulin (IVIG). For an early diagnosis and treatment, PSPC should be included in the list of malignancies that cause PCD with anti-Yo antibodies.

責任著者(Corresponding author)

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