Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918

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Two Cases of Gastric Adenocarcinoma with Enteroblastic Differentiation which Demonstrated Rapid Progressive Courses
Sho MatsuyamaAkihisa FukudaAtsushi MatsumotoTaro UeoMasaya OhanaHiroshi Seno
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ジャーナル オープンアクセス 早期公開

論文ID: 3913-24

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We herein report two extremely rare cases of gastric adenocarcinoma with enteroblastic differentiation (GAED) that underscore the aggressive nature of GAED.

Case 1: ESD was scheduled for early-stage gastric cancer, however, the tumor increased in size drastically and the morphology changed to type "0-I + IIc" in one month. Surgery was performed and the patient was diagnosed with GAED.

Case 2: ESD was performed for early-stage gastric cancer, and the pathological findings revealed GAED. The horizontal margin was positive for clear cells in the muscularis mucosa. Additional surgery was performed; however, recurrence occurred one year later.

Therefore, the treatment strategies should be carefully considered for GAED.

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© 2024 by The Japanese Society of Internal Medicine

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