The First Case Report of Acute Symptomatic HEV Genotype 4 Infection in an HIV-positive Patient in Japan

Satoshi Kitaura; Yoshitaka Wakabayashi; Aiko Okazaki; Yuta Okada; Koh Okamoto; Mahoko Ikeda; Shu Okugawa; Kyoji Moriya

doi:10.2169/internalmedicine.4505-20

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The First Case Report of Acute Symptomatic HEV Genotype 4 Infection in an HIV-positive Patient in Japan

Satoshi Kitaura, Yoshitaka Wakabayashi, Aiko Okazaki, Yuta Okada, Koh Okamoto, Mahoko Ikeda, Shu Okugawa, Kyoji Moriya

著者情報

Satoshi Kitaura
Department of Infectious Diseases, The University of Tokyo Hospital, Japan
Yoshitaka Wakabayashi
Department of Infectious Diseases, The University of Tokyo Hospital, Japan
Department of Internal Medicine, Teikyo University, Japan
Aiko Okazaki
Department of Infectious Diseases, The University of Tokyo Hospital, Japan
Yuta Okada
Department of Infectious Diseases, The University of Tokyo Hospital, Japan
Koh Okamoto
Department of Infectious Diseases, The University of Tokyo Hospital, Japan
Mahoko Ikeda
Department of Infection Control and Prevention, The University of Tokyo, Japan
Shu Okugawa
Department of Infectious Diseases, The University of Tokyo Hospital, Japan
Kyoji Moriya
Department of Infectious Diseases, The University of Tokyo Hospital, Japan
Department of Infection Control and Prevention, The University of Tokyo, Japan

キーワード: hepatitis E, hepatitis E virus, human immunodeficiency virus, men who have sex with men

ジャーナルオープンアクセス早期公開

論文ID: 4505-20

DOI https://doi.org/10.2169/internalmedicine.4505-20

この記事には本公開記事があります。

The final version of this article is now available: Vol. 59 (2020), No. 13 pp. 1655-1658

詳細

抄録

Hepatitis E virus (HEV) is a common cause of acute hepatitis. Four major genotypes of HEV have been studied, with genotype 4 being the predominant genotype across Asia. We herein describe the case of a 50-year-old man with a history of human immunodeficiency virus (HIV) infection who was admitted with acute transaminitis. Serum anti-HEV-IgA and HEV-RNA were detected at the time of presentation and further testing revealed HEV genotype 4. To the best of our knowledge, this represents the first clinical case report of acute symptomatic HEV genotype 4 infection in an HIV-positive patient in Japan.

責任著者(Corresponding author)

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