A Case of Subacute Combined Degeneration of the Spinal Cord Caused by Autoimmune Gastritis

Kazuhiro Ota; Ryosuke Yamaguchi; Akihiro Tsukahara; Shinya Nishida; Taro Shigekiyo; Satoshi Harada; Yuichi Kojima; Toshihisa Takeuchi; Shigeki Arawaka; Kazuhide Higuchi

doi:10.2169/internalmedicine.4684-20

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引用する場合も本公開記事を引用してください。

A Case of Subacute Combined Degeneration of the Spinal Cord Caused by Autoimmune Gastritis

Kazuhiro Ota, Ryosuke Yamaguchi, Akihiro Tsukahara, Shinya Nishida, Taro Shigekiyo, Satoshi Harada, Yuichi Kojima, Toshihisa Takeuchi, Shigeki Arawaka, Kazuhide Higuchi

著者情報

キーワード: autoimmune gastritis, vitamin B₁₂ deficiency, subacute combined degeneration of spinal cord, peripheral neuropathy

ジャーナルオープンアクセス早期公開

論文ID: 4684-20

DOI https://doi.org/10.2169/internalmedicine.4684-20

この記事には本公開記事があります。

The final version of this article is now available: Vol. 59 (2020), No. 17 pp. 2113-2116

詳細

抄録

A 68-year-old woman presented with a 2-year history of worsening unsteady gait. Her neurological examination revealed peripheral neuropathy with lower limb sensory dominance. T2-weighted imaging revealed a disorder of the posterior cervical cord. Blood test findings revealed vitamin B₁₂ deficiency, and gastroscopy revealed typical findings of autoimmune gastritis. She received vitamin B₁₂ supplementation, but some peripheral neuropathy symptoms persisted due to longstanding vitamin B₁₂ deficiency. Asymptomatic patients should undergo gastroscopy to detect autoimmune gastritis, as chronic vitamin B₁₂ deficiency causes irreversible peripheral neuropathy.

責任著者(Corresponding author)

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