Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918

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Role of Random Skin Biopsies in the Diagnosis of Aortic Angiosarcoma
Tomohiro MiyamuraKen YoshidaTaizo ShimomuraToshikazu MiyakawaHitoshi SuzushimaKenichiro TanakaMio OhshiroMayuko MoritsuboKoichi Ohshima
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ジャーナル オープンアクセス 早期公開

論文ID: 4879-24

この記事には本公開記事があります。
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Aortic angiosarcoma is an extremely rare malignancy that is often diagnosed postoperatively or during autopsy. We present a case that was diagnosed through random skin biopsy. A 75-year-old woman with Alzheimer's disease and chronic kidney disease presented with persistent fever and elevated C-reactive protein levels. Contrast-enhanced computed tomography showed irregular thickening of the aortic wall, which was initially suspected to be atherosclerosis. A random skin biopsy revealed tumor cells that were positive for vascular endothelial markers. The patient died 69 days later, with an autopsy confirming aortic angiosarcoma. Random skin biopsies may aid in the diagnosis of aortic angiosarcoma by detecting metastatic lesions when invasive procedures are not feasible.

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© 2025 by The Japanese Society of Internal Medicine

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