Auto Immune Glial Fibrillary Acidic Protein Astrocytopathy Coexistent with Positivity for Anti-NH2-terminal of α-enolase Antibodies: A Case Report

Junichi Matsuo; Satoshi Namitome; Yasuyuki Hara; Tadashi Terasaki; Makoto Nakajima; Mitsuharu Ueda

doi:10.2169/internalmedicine.5528-25

Auto Immune Glial Fibrillary Acidic Protein Astrocytopathy Coexistent with Positivity for Anti-NH₂-terminal of α-enolase Antibodies: A Case Report

Junichi Matsuo, Satoshi Namitome, Yasuyuki Hara, Tadashi Terasaki, Makoto Nakajima, Mitsuharu Ueda

著者情報

キーワード: Glial fibrillary acidic protein astrocytopathy, autoimmune meningoencephalitis/myelitis, anti-NH₂-terminal of α-enolase, urinary retention, Hashimoto's encephalopathy

ジャーナルオープンアクセス早期公開

論文ID: 5528-25

DOI https://doi.org/10.2169/internalmedicine.5528-25

詳細

抄録

A 46-year-old woman presented with acute disturbance of consciousness, ataxia, and urinary retention. Although Hashimoto's encephalopathy was initially suspected due to the detection of serum anti-NH₂-terminal α-enolase (NAE) antibodies, glial fibrillary acidic protein (GFAP)-astrocytopathy was also considered probable due to urinary retention. An additional examination revealed positive results for both anti-GFAP and anti-NAE antibodies. This case highlights the importance of considering antibodies to be examined based on clinical features, even in the presence of antibodies.

責任著者(Corresponding author)

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