Utility of Endoscopic Ultrasound with Bronchoscope-guided Fine-needle Aspiration for Detecting Driver Oncogenes in Non-small-cell Lung Cancer During Emergency Situations: Case Series

Koki Nakashima; Yoshiki Demura; Masahiro Oi; Mio Tabata; Toshihiko Tada; Kohei Shiozaki; Masaya Akai; Tamotsu Ishizuka

doi:10.2169/internalmedicine.5594-20

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引用する場合も本公開記事を引用してください。

Utility of Endoscopic Ultrasound with Bronchoscope-guided Fine-needle Aspiration for Detecting Driver Oncogenes in Non-small-cell Lung Cancer During Emergency Situations: Case Series

Koki Nakashima, Yoshiki Demura, Masahiro Oi, Mio Tabata, Toshihiko Tada, Kohei Shiozaki, Masaya Akai, Tamotsu Ishizuka

著者情報

Koki Nakashima
Department of Respiratory Medicine, Japanese Red Cross Fukui Hospital, Japan
Third department of Internal medicine, Faculty of Medical Sciences, University of Fukui, Japan
Yoshiki Demura
Department of Respiratory Medicine, Japanese Red Cross Fukui Hospital, Japan
Masahiro Oi
Department of Respiratory Medicine, Japanese Red Cross Fukui Hospital, Japan
Mio Tabata
Department of Respiratory Medicine, Japanese Red Cross Fukui Hospital, Japan
Toshihiko Tada
Department of Respiratory Medicine, Japanese Red Cross Fukui Hospital, Japan
Kohei Shiozaki
Department of Respiratory Medicine, Japanese Red Cross Fukui Hospital, Japan
Masaya Akai
Department of Respiratory Medicine, Japanese Red Cross Fukui Hospital, Japan
Tamotsu Ishizuka
Third department of Internal medicine, Faculty of Medical Sciences, University of Fukui, Japan

キーワード: non-small-cell lung cancer, EUS-B-FNA, EGFR, ALK, driver oncogene, oncologic emergency

ジャーナルオープンアクセス早期公開

論文ID: 5594-20

DOI https://doi.org/10.2169/internalmedicine.5594-20

この記事には本公開記事があります。

The final version of this article is now available: Vol. 60 (2021), No. 7 pp. 1061-1065

詳細

抄録

Since it is difficult to obtain tumor tissue via airway observation for lung cancer patients with a poor respiratory condition, endoscopic ultrasound with bronchoscope-guided fine-needle-aspiration (EUS-B-FNA), a transesophageal procedure, is effective for such patients.

We herein report three patients with driver oncogenes taken to the emergency department because of lung cancer-related symptoms. EUS-B-FNA was performed because of the patients' poor respiratory conditions to detect driver oncogenes. The general conditions improved, and the patients achieved a long-term survival with tyrosine kinase inhibitors. Our findings suggest that EUS-B-FNA should be considered to detect driver oncogenes in lung cancer patients despite poor respiratory conditions in emergency departments.

責任著者(Corresponding author)

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