Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918

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Antimitochondrial Antibody-associated Myopathy with Slowly Progressive Cardiac Dysfunction: A Case Report
Fumihiko TakahashiJun SawadaAkiho MinoshimaNaka SakamotoToshiyuki OnoKazumi AkasakaHidehiro TakeiIchizo NishinoNaoyuki Hasebe
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ジャーナル オープンアクセス 早期公開

論文ID: 5600-20

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A 45-year-old woman was referred to our hospital for the evaluation of proximal muscle weakness and serum creatinine kinase elevation. She had atrial fibrillation and left ventricular asynergy. She was diagnosed with myopathy, accompanied by cardiomyopathy of unknown etiology. She was treated with prednisolone. After long-term follow-up and a detailed examination, the patient was diagnosed with antimitochondrial antibody (AMA)-associated myopathy with cardiac involvement. Although the patient received medical treatment, including beta-blockers and prednisolone, her cardiac function deteriorated progressively. Physicians should consider AMA-associated myopathy when diagnosing myopathies of unknown etiology. The presence of cardiac involvement should be proactively investigated in AMA-associated myopathy.

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© 2021 by The Japanese Society of Internal Medicine
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