A Case of Nodular Pulmonary Sarcoidosis with a B Cell Reaction Similar to That of IgG4-related Disease

Hirokazu Tokuyasu; Shuichi Matsuoka; Katsunori Arai; Hiromitsu Sakai; Ken Miwa; Chika Esumi; Akira Yamasaki

doi:10.2169/internalmedicine.6009-25

Hirokazu Tokuyasu, Shuichi Matsuoka, Katsunori Arai, Hiromitsu Sakai, Ken Miwa, Chika Esumi, Akira Yamasaki

著者情報

キーワード: Anti-neutrophil cytoplasmic antibody, IgG4-related disease, Non-caseating granuloma, Pulmonary nodular sarcoidosis

ジャーナルオープンアクセス早期公開

論文ID: 6009-25

DOI https://doi.org/10.2169/internalmedicine.6009-25

詳細

抄録

A 66-year-old man presented to our hospital following the detection of abnormal chest shadows during a previous medical checkup. Chest computed tomography revealed multiple small nodules in both lungs, and surgical biopsy was performed for the diagnosis. A histological examination of the pulmonary nodules revealed small non-caseating epithelioid cell granulomas with prominent infiltration of lymphocytes and IgG4-positive plasma cells. The patient was eventually diagnosed with pulmonary sarcoidosis, with a B-cell response similar to that of IgG4-related disease. This report provides insight into sarcoidosis with histopathological features similar to those of IgG4-related diseases.

責任著者(Corresponding author)

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