Long Spinal Cord Lesions Caused by Venous Congestive Myelopathy Associated with Intravascular Large B-cell Lymphoma

Takeshi Miura; Shoji Saito; Rie Saito; Tomohiro Iwasaki; Naomi Mezaki; Tomoe Sato; Yoichi Ajioka; Akiyoshi Kakita; Takuya Mashima

doi:10.2169/internalmedicine.6717-20

この記事には本公開記事があります。本公開記事を参照してください。
引用する場合も本公開記事を引用してください。

Long Spinal Cord Lesions Caused by Venous Congestive Myelopathy Associated with Intravascular Large B-cell Lymphoma

Takeshi Miura, Shoji Saito, Rie Saito, Tomohiro Iwasaki, Naomi Mezaki, Tomoe Sato, Yoichi Ajioka, Akiyoshi Kakita, Takuya Mashima

著者情報

Takeshi Miura
Department of Neurology, Tsubame Rosai Hospital, Japan
Shoji Saito
Department of Pathology, Brain Research Institute, Niigata University, Japan
Department of Neurosurgery, Brain Research Institute, Niigata University, Japan
Rie Saito
Department of Pathology, Brain Research Institute, Niigata University, Japan
Tomohiro Iwasaki
Department of Internal medicine, Tsubame Rosai Hospital, Japan
Naomi Mezaki
Department of Neurology, Tsubame Rosai Hospital, Japan
Tomoe Sato
Department of Neurology, Tsubame Rosai Hospital, Japan
Yoichi Ajioka
Division of Molecular and Diagnostic Pathology Graduate School of Medical and Dental Sciences, Niigata University, Japan
Akiyoshi Kakita
Department of Pathology, Brain Research Institute, Niigata University, Japan
Takuya Mashima
Department of Neurology, Tsubame Rosai Hospital, Japan

キーワード: intravascular lymphoma, IVL, IVLBCL, MALT lymphoma, long spinal cord lesion, venous congestive myelopathy

ジャーナルオープンアクセス早期公開

論文ID: 6717-20

DOI https://doi.org/10.2169/internalmedicine.6717-20

この記事には本公開記事があります。

The final version of this article is now available: Vol. 60 (2021), No. 23 pp. 3809-3816

詳細

抄録

Intravascular large B-cell lymphoma (IVLBCL) is a subtype of B-cell lymphoma, characterized by lymphoma cell proliferation within small blood vessels. We herein describe a rare case with long spinal cord lesions caused by venous congestive myelopathy associated with IVLBCL. An 81-year-old man presented with paraplegia of the lower limbs and sensory disturbances. Magnetic resonance imaging revealed intramedullary longitudinal T2-hyperintensity lesions in the thoracic cords. The patient died three months after disease onset, and a neuropathological analysis revealed predominantly atypical B-lymphocytes located sparsely in the veins of the spinal cord. IVLBCL should be considered in the differential diagnoses of long spinal cord lesions.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）