Paradoxical Formation of a Pleuroparenchymal Fibroelastosis-like Lesion in the Chronic Course of Pulmonary Sarcoidosis

Michiru Sawahata; Takeshi Johkoh; Takeshi Kawanobe; Chiyoko Kono; Takuji Suzuki; Masashi Bando; Koichi Hagiwara; Noriharu Shijubo; Satoshi Konno; Tetsuo Yamaguchi

doi:10.2169/internalmedicine.8074-21

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Paradoxical Formation of a Pleuroparenchymal Fibroelastosis-like Lesion in the Chronic Course of Pulmonary Sarcoidosis

Michiru Sawahata, Takeshi Johkoh, Takeshi Kawanobe, Chiyoko Kono, Takuji Suzuki, Masashi Bando, Koichi Hagiwara, Noriharu Shijubo, Satoshi Konno, Tetsuo Yamaguchi

著者情報

Michiru Sawahata
Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan
Department of Respiratory Medicine, National Hospital Organization Utsunomiya National Hospital, Japan
Takeshi Johkoh
Department of Radiology, Kansai Rosai Hospital, Japan
Takeshi Kawanobe
Department of Respiratory Medicine, JR Tokyo General Hospital, Japan
Chiyoko Kono
Department of Respiratory Medicine, JR Tokyo General Hospital, Japan
Takuji Suzuki
Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan
Masashi Bando
Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan
Koichi Hagiwara
Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan
Noriharu Shijubo
Department of Respiratory Medicine, JR Sapporo Hospital, Japan
Satoshi Konno
Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan
Tetsuo Yamaguchi
Shinjuku Tsurukame Clinic, Japan

キーワード: sarcoidosis, pleuroparenchymal fibroelastosis, non-caseating epithelioid granuloma, pleural thickening, subpleural consolidation

ジャーナルオープンアクセス早期公開

論文ID: 8074-21

DOI https://doi.org/10.2169/internalmedicine.8074-21

この記事には本公開記事があります。

The final version of this article is now available: Vol. 61 (2022), No. 4 pp. 523-526

詳細

抄録

We herein report the long-term changes in chest computed tomography (CT) findings from early sarcoidosis lesions to pleuroparenchymal fibroelastosis (PPFE)-like lesions in a 30-year-old man with granulomas on a transbronchial lung biopsy. Multiple bilateral micronodular and nodular opacities around the bronchovascular bundle in the upper lobes detected by chest CT in 2004 disappeared, but paradoxically, peripheral consolidations continued to grow at the periphery of the original lesions. Chest CT in 2017 confirmed the progression of bilateral shrinkage of the upper lobe, spread of peripheral consolidations and wedge-shaped opacities below the first rib, and bronchiectatic air bronchograms, confirming PPFE-like lesions.

責任著者(Corresponding author)

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