Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918

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SARS-CoV-2-related Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease: A Case Report and Literature Review
Toshihiro IdeTakeru KawanamiMakoto EriguchiHideo Hara
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ジャーナル オープンアクセス 早期公開

論文ID: 8709-21

この記事には本公開記事があります。
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We herein report a case of MOG antibody-associated disease after SARS-CoV-2 infection. A 24-year-old woman developed unilateral optic neuritis 3 weeks after contracting COVID-19, followed by intracranial demyelinating lesions and myelitis. Since serum anti-MOG antibody was positive, we diagnosed MOG antibody-associated disease. Immunotherapy with steroids resulted in the rapid improvement of neurological symptoms. This is a suggestive case, as there are no reports of MOG antibody-associated disease with multiple neurological lesions occurring after COVID-19. The response to immunotherapy was favorable. This case suggests that it is important to measure anti-MOG antibodies in patients who develop inflammatory neurological disease after COVID-19.

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© 2022 by The Japanese Society of Internal Medicine
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