A Case of a Pregnant Woman with IgA Nephropathy Showing Histological Preeclampsia Findings without Hypertension Treated with Steroids: A Case Report and Literature Review

Nagisa Koda; Kei Matsumoto; Yukio Maruyama; Naomi Ishikawa; Nobuo Tsuboi; Tetsuya Kawamura; Takashi Yokoo

doi:10.2169/internalmedicine.9146-21

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A Case of a Pregnant Woman with IgA Nephropathy Showing Histological Preeclampsia Findings without Hypertension Treated with Steroids: A Case Report and Literature Review

Nagisa Koda, Kei Matsumoto, Yukio Maruyama, Naomi Ishikawa, Nobuo Tsuboi, Tetsuya Kawamura, Takashi Yokoo

著者情報

キーワード: preeclampsia, IgA nephropathy, gestational proteinuria

ジャーナルオープンアクセス早期公開

論文ID: 9146-21

DOI https://doi.org/10.2169/internalmedicine.9146-21

この記事には本公開記事があります。

The final version of this article is now available: Vol. 62 (2023), No. 8 pp. 1195-1202

詳細

抄録

A 35-year-old woman pregnant with twins developed nephrotic syndrome (NS) at 33 weeks' gestation, but her blood pressure remained within the normal range throughout gestation and puerperium. At 34 weeks' gestation, she delivered healthy twins via Caesarean section. After delivery, she developed massive proteinuria (21.1 g/day) and severe hypoalbuminemia (1.0 g/dL). A renal biopsy performed 19 days after delivery revealed IgA nephropathy (IgAN) and preeclampsia. She was treated with steroids, and the NS gradually resolved. This is a rare case of massive gestational proteinuria with IgAN and preeclampsia pathologically that did not meet the clinical criteria for preeclampsia.

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