Severe Immune Thrombocytopenia after COVID-19 Vaccination: Two Case Reports and a Literature Review

Takuto Shonai; Fumihiko Kimura; Junichi Watanabe

doi:10.2169/internalmedicine.9177-21

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Severe Immune Thrombocytopenia after COVID-19 Vaccination: Two Case Reports and a Literature Review

Takuto Shonai, Fumihiko Kimura, Junichi Watanabe

著者情報

キーワード: immune thrombocytopenia, vaccination, COVID-19

ジャーナルオープンアクセス早期公開

論文ID: 9177-21

DOI https://doi.org/10.2169/internalmedicine.9177-21

この記事には本公開記事があります。

The final version of this article is now available: Vol. 61 (2022), No. 10 pp. 1581-1585

詳細

抄録

We herein report two cases of coronavirus disease 2019 (COVID-19) vaccine-induced immune thrombocytopenia (ITP). A 69-year-old Japanese man developed severe thrombocytopenia after COVID-19 vaccination. He had oral bleeding and hemoptysis but no thrombotic symptoms. He improved rapidly with oral prednisolone therapy. A 34-year-old Japanese woman had generalized purpura after COVID-19 vaccination. Her platelet count improved rapidly after treatment with prednisolone and eltrombopag. The occurrence of two cases of ITP after COVID-19 vaccination at a single institution suggests that there could be more such undiagnosed cases, especially cases of mild secondary ITP.

責任著者(Corresponding author)

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