Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhaging Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation

Soichi Ohta; Takeo Matsuyoshi; Hitoshi Kaneko; Daiyu Kosen; Hiroaki Suzuki; Jun Hamaguchi; Yuichi Sato; Keiki Shimizu

doi:10.2169/internalmedicine.9472-22

この記事には本公開記事があります。本公開記事を参照してください。
引用する場合も本公開記事を引用してください。

Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhaging Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation

Soichi Ohta, Takeo Matsuyoshi, Hitoshi Kaneko, Daiyu Kosen, Hiroaki Suzuki, Jun Hamaguchi, Yuichi Sato, Keiki Shimizu

著者情報

Soichi Ohta
Emergency and Critical Care Center, Tokyo Metropolitan Tama Medical Center, Japan
Takeo Matsuyoshi
Emergency and Critical Care Center, Tokyo Metropolitan Tama Medical Center, Japan
Hitoshi Kaneko
Emergency and Critical Care Center, Tokyo Metropolitan Tama Medical Center, Japan
Daiyu Kosen
Emergency and Critical Care Center, Tokyo Metropolitan Tama Medical Center, Japan
Hiroaki Suzuki
Emergency and Critical Care Center, Tokyo Metropolitan Tama Medical Center, Japan
Jun Hamaguchi
Emergency and Critical Care Center, Tokyo Metropolitan Tama Medical Center, Japan
Yuichi Sato
Emergency and Critical Care Center, Tokyo Metropolitan Tama Medical Center, Japan
Keiki Shimizu
Emergency and Critical Care Center, Tokyo Metropolitan Tama Medical Center, Japan

キーワード: diffuse alveolar hemorrhaging, myeloperoxidase anti-neutrophil cytoplasmic autoantibody-associated vasculitis, extracorporeal membrane oxygenation

ジャーナルオープンアクセス早期公開

論文ID: 9472-22

DOI https://doi.org/10.2169/internalmedicine.9472-22

この記事には本公開記事があります。

The final version of this article is now available: Vol. 61 (2022), No. 23 pp. 3569-3573

詳細

抄録

Regarding extracorporeal membrane oxygenation (ECMO) support against hemorrhagic conditions, there seems to be a dilemma when deciding between maintaining the circuit patency by systemic anticoagulation and increasing the risk of bleeding. We herein report two cases of diffuse alveolar hemorrhaging (DAH) caused by myeloperoxidase (MPO) anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) successfully treated with venovenous (VV)-ECMO support, both initially started without systemic anticoagulation. Under anticoagulation-free ECMO management, we should consider the shortcomings of frequent circuit exchange and hemorrhagic diathesis related to circuit-induced disseminated intravascular coagulation (DIC).

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）