Late-Onset Homozygous Protein C Deficiency Manifesting Cerebral Infarction as the First Symptom at Age 27

Katsumi DEGUCHI; Tetsuya TSUKADA; Eiichi IWASAKI; Hideo WADA; Seiko MURASHIMA; Masao MIYAZAKI; Shigeru SHIRAKAWA

doi:10.2169/internalmedicine.31.922

Katsumi DEGUCHI, Tetsuya TSUKADA, Eiichi IWASAKI, Hideo WADA, Seiko MURASHIMA, Masao MIYAZAKI, Shigeru SHIRAKAWA

著者情報

キーワード: DIC, thrombosis, low molecular weight heparin, cerebrovascular disease

ジャーナルフリー

1992 年 31 巻 7 号 p. 922-925

DOI https://doi.org/10.2169/internalmedicine.31.922

詳細

抄録

We report a 31-year-old female who had repeated thrombosis and was diagnosed as having congenital homozygous protein C deficiency based on decreased protein C antigen and activity, and the findings of family history. This patient had shown no symptom of thrombosis until the age of 27 years, when she had cerebral infarction as the first symptom. Low molecular weight heparin was useful for disseminated intravascular coagulation (DIC) that complicated protein C deficiency in this patient.
(Internal Medicine 31 : 922-925, 1992)

責任著者(Corresponding author)

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