Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Minocycline-Induced Pneumonitis with Bilateral Hilar Lymphadenopathy and Pleural Effusion
Takuma BANDOMasaki FUJIMURAYatsugi NODAJin-ichiro HIROSEGoroku OHTATamotsu MATSUDA
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1994 年 33 巻 3 号 p. 177-179

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A 65-year-old man developed respiratory failure with diffuse interstitial shadow, bilateral pleural effusion, and bilateral hilar lymphadenopathy on chest X-ray and CT, after intravenous administration of minocycline. Corticosteroid therapy was effective. The findings from bronchoalveolar lavage (BAL) and transbronchial lung biopsy were compatible with eosinophilic pneumonia. Provocation test supported this diagnosis, but the lymphocyte stimulation test was negative. A review of the literature and the diagnoses of drug-induced pulmonary diseases are discussed.
(Internal Medicine 33:177-179, 1994)

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