Adult Respiratory Distress Syndrome with Increased Serum and Bronchoalveolar Lavage Fluid Levels of Squamous Cell Carcinoma-Related Antigen

Jun-ichi ASHITANI; Hiroshi MUKAE; Hirotoshi IHIBOSHI; Haruko TANIGUCHI; Hideo MASHIMOTO; Shigeru MATSUKURA

doi:10.2169/internalmedicine.35.497

Jun-ichi ASHITANI, Hiroshi MUKAE, Hirotoshi IHIBOSHI, Haruko TANIGUCHI, Hideo MASHIMOTO, Shigeru MATSUKURA

著者情報

キーワード: adult respiratory distress syndrome (ARDS), neutrophil elastase, squamous cell carcinoma-related antigen (SCC), interleukin (IL)-8

ジャーナルフリー

1996 年 35 巻 6 号 p. 497-501

DOI https://doi.org/10.2169/internalmedicine.35.497

詳細

抄録

We report a case with adult respiratory distress syndrome (ARDS) associated with increased levels of squamous cell carcinoma-related antigen (SCC) in the serum and bronchoalveolar lavage fluid (BALF). ARDS was likely induced by ibuprofen, based on the presence of pancytopenia and a weakly positive drug lymphocyte stimulating test (DLST). High serum and BALF levels of interleukin (IL)-8, neutrophil elastase as well as SCC were detected. Corticosteroid therapy resulted in clinical improvement, resolution of pulmonary infiltrates on chest roentgenogram and normalization of serum and BALF levels of IL-8, neutrophil elastase and SCC.
(Internal Medicine 35: 497-501, 1996)

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