抄録
One thousand and one hundred seventy seven strains of Micrococcus pyogenes were collected at 15 National Hospitals of Japan from August 1957 to July 1958, participating in the Society for Micrococcus Research. 1, 100 phage-typable strains (coagulase positive strains and a coagulase negative strain) were tested for antibiotic resistance and abcteriophagetyping.
(1) Resistance to antibiotics. (Pc. SM. CM. TC. EM.)
62.8% of the strains collected from infections and 39.2% of those from carriers were over 1 unit per ml Pc.. 28.2% of the strains collected from infections and 29.1% of those from carriers were over l0mcg per ml SM.. 23.8% of the strains collected from infections and 16.1% of those from carriers were over 3 mcg per ml TC, and 13.5% of the former and 13.7% of the latter were over 10mcg per ml.
Resistant strains over 10mcg per ml CM, and over 1 mcg per ml EM, were very few.
If above mentioned density of antibiotics were considered as the limit of the resistance, relation between the resistant strains and the antibiotics were different by each hospital; in Kanto District large number of resistant strains, and higher resistant strains were found, but in Chugoku District they were very few.
Resistant strains to several antibiotics were also of higher resistant to each antibiotics. There was a large number of strains, such as Pc-SM, of Pc-TC, resistant strains; and 10% of all strains were Pc-SM-TC resistant, but resistant strains to four antibiotics were very few.
(2) Bacteriophage-typing
Typable strains were 60-70% of all the strains. In infections, the II group was much found and the number of each group was in order of II, III and I. In carriers group III was found frequently and the number of each group was in order of groups III, II, mixed, and I. In Kanto District, group I was found, but in Chugoku and Kyushu District very few.
(3) Relation between phage-types and antibiotic-resistances.
In both Pc. and SM, group I was found frequently in resistant strains, and group II in sensitive strains.
Not-typable strains were found in higher resistant strains and in the resistant strains to several antibiotics (Pc. SM. TC.).
