抄録
It is practically very hard to collect all data on the reactions caused by mixing of injections in various combination. Then, from the view-point that the changes by mixing may be conjectured to some extent from the physical and chemical characters of each injection to be combined, the interrelation between the measured data on the characters of certain injections and the changes caused by mixing them was studied.
In the first year, next two subjects were carried out. First, all prescriptions of injection ordered for a week were inquired of all national hospitals. 1 Secondly, several characters of individual injection such as pH, capillary action, turbidity, viscosity, color tone and reaction to acid and alkali were actually measured.
The following facts were learned upon the inquiry:
1) The infusion solution used in the mixed injection was almost one kind, mainly glucose or xylitol solution, which was occupied 88 %.
2) The injection mixed to infusion solution was overwhelmingly ascorbic acid.
3) The injections (including infusion solution) used in the mixed injection was mostly 4 kinds and was 4.72 kinds on the average. This average number was nearly consistent with 5 kinds on the average reported in the meeting of Japan Pharmaceutical Association.
4) 21 kinds of injections were mixed in the most Case.
The main results obtained by the actual measurement of several characters of individual injection were as follows:
1) Most of pH was kept arround neutral.
2) There were 48 injections reacted peculiarly to acid or alkali.
3) There were 67 injections to be confirmed containing stabilizer or antiseptic.
