抄録
X-ray intravital microscopy using a microangiography technique was developed at SPring-8 to enable in vivo visualization of coronary arteries for vascular-based functional imaging in rats and mice. Angiographic images of beating hearts were obtained with spatial resolution in the micrometer range and temporal resolution in the millisecond range. Small blood vessels around 50 µm in diameter were visualized clearly. The X-ray intravital microscopy enables direct investigation of vascular functions.