The discussion in this article is based on a hypothesis as follows. If all of the members of a corporation have shared ethical value as organizational culture to such an extent that the corporation reflects the value into the corporate strategy, the powerful corporate competitiveness will be created. This article analyzes ethical matter in pharmaceutical company, and argues some framework of the effective use of ethical value in organization. Furthermore, the framework is applied to the cases of the strategic responses by pharmaceutical companies in the harmful effect of medicine.