Abstract
The continuous production of cyclodextrins (CD) using the ultrafiltration (UF) is described. This expperiment is based on the use of the membrane reactor system in which UF membrane modules, having the cut off molecular weight 100, 000 each, are equipped. The experimental procedures were as follows. Cyclodextrins mixture was prepared by the action of Bacillus macerans cycladextrin glucanotransferase on liquefied potato starch. This reaction mixture was pumped up to and recycled through the UF membrane reactor system. On the other hand, during the above mentioned operation, liquefied potato starch solution which was prepared by the continuous liquefying equipment was supplied continuously to the system as much as the volume of the permeate from the UF modules. The experiments were carried out for 6 days as the 1 cycle.
As the result, the recovery of CD in the permeate filtrate was 73% and the total yield of CD was 65.6%. The reaction efficiency of this continuous UF membrane reactor system was 2.6 times higher than that of the batch operation.
