Journal of Oral Tissue Engineering
Online ISSN : 1880-0823
Print ISSN : 1348-9623
ISSN-L : 1348-9623
ORIGINAL ARTICLES
In Vitro Study of Cell Differentiation by Two Type Mouse Embryo Stem Cells on the Dental Adhesives
Koichi IMAIKazuhiko SUESEYoshitomo HONDATsubasa SHIRAIFumiya OGAWAHirofumi SAWAIHiromasa TAKASHIMA
著者情報
ジャーナル フリー

2014 年 12 巻 2 号 p. 85-92

詳細
抄録
Embryonic Stem Cell Test (EST) is an in vitro embryotoxicity screening test to predict human developmental toxicity, mainly used in Europe and the United States. In the present study, EL-M3 and ES-R1-EGFP B2/EGFP cell lines were used, instead of the mouse ES-D3 cell line that is used as an indicator of cell differentiation, to compare the developmental toxicities of 11 dental adhesives with those obtained with ES-D3 cells. The results were comparable between EL-M3 and ES-D3 cell lines. Specifically, all the products fall into the category of "non- embryotoxicity," although the results widely varied. Three-dimensional culture with glass fibers could also be employed for the experiment.
著者関連情報
© 2014 by Japanese Association of Regenerative Dentistry
前の記事 次の記事
feedback
Top