抄録
In studying the drug treatment of dyslipidemias or dyslipoproteinemias, we observed several patterns of reactions common to the different kinds of drugs and populations. They were: (i) when we classified dyslipidemias according to the grade of severity, higher the grade of severity, always greater the response to a treatment, (ii) namely, higher the baseline level, greater the change in reduction, (iii) there was a turning point of effect where the reaction to the drug treatment became zero and hereafter the sign of the reaction reversed, (iv) if we treated hypolipidemias with the same lipid lowering drug, they reacted to the drug in the direction to raise the low serum lipids.
These patterns of the reactions indicated that there exists a certain level where all the dyslipidemias tend to converge as the result of drug treatment. We formulated the method to estimate the convergent level and considered it as a homeostatic level of human serum lipid and lipoproteins.
