動脈硬化(特に冠動脈硬化)とアポ蛋白
1987 年 15 巻 5 号 p. 1125-1130
詳細
1987 年 15 巻 5 号 p. 1125-1130
Multiple regression analysis of 16 risk factors, including serum apolipoproteins in angiographically measured coronary stenosis, was carried out in 291 consecutive patients (190 males and 101 females).
The risk factors were age, total cholesterol (TC), triglycerides (TG), high density lipoprotein-choles-terol (HDL-C), HDL-C/TC, apolipoprotein A-I, A-II, B, C-II, C-III, E, B/A-I, smoking, weight index (WI), glucose tolerance (GT), and blood pressure (BP).
Severity of coronary atherosclerosis was scored as the extent of disease seen at arteriography (coronary score: CS).
The order of importance of risk factors to CS in the five groups of subjects studied were as follows, (1) All subjects: TC>smoking>A-I*gt;age>GT, (2) Male group: TC<A-I>smoking>age, (3) Female group: smoking>age, (4) Young group (age below 54 years): smoking<B/A-I>BP, and (5) Old group (age over 55 years): TC>smoking>A-I>GT.
