Journal of Clinical Biochemistry and Nutrition
Online ISSN : 1880-5086
Print ISSN : 0912-0009
ISSN-L : 0912-0009
Original Articles
Effects of Astaxanthin on Human Blood Rheology
Hiromi MiyawakiJiro TakahashiHiroki TsukaharaIsao Takehara
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2008 Volume 43 Issue 2 Pages 69-74


Effects of astaxanthin (AX) derived from H. pluvialis on human blood rheology were investigated in 20 adult men with a single-blind method. The experimental group was 57.5 ± 9.8 years of age and the placebo group was 50.8 ± 13.1 years of age. A blood rheology test that measures whole blood transit time was conducted using heparinized blood of the volunteers by a MC-FAN apparatus (microchannel array flow analyzer). After administration of AX 6 mg/day for 10 days, the values of the experimental group were decreased from 52.8 ± 4.9 s to 47.6 ± 4.2 s (p<0.01) and a comparison of the values between the experimental (47.6 ± 4.2 s) and the placebo (54.2 ± 6.7 s) groups showed a significant difference (p<0.05). There were no adverse effects resulting from the administration of AX 6 mg/day for 10 days. Informed consent was obtained from each subject.

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© 2008 by The Editorial Secretariat of JCBN
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