Effect of Syzigium cumini in Plasma Antioxidants on Alloxan-Induced Diabetes in Rats
1998 年 25 巻 2 号 p. 81-86
詳細
1998 年 25 巻 2 号 p. 81-86
We undertook the present study to evaluate the antioxidant activity of an aqueous extract of the seeds of Syzigium cumini, an indigenous plant present in different parts of India, South-East Asia and Eastern Africa, toward experimental diabetes. Administration of the extract for 6 weeks resulted in significant reductions in plasma lipid peroxide, ceruloplasmin and α-tocopherol and a significant elevation in plasma reduced glutathione and vitamin C in alloxan diabetic rats. Insulin restored all the parameters to their normal values. The seed extract was also more effective than glibenclamide in restoring the values of these parameters.
