連載企画 X線結晶学者のためのクライオ電子顕微鏡解析の手引き
クライオ電子顕微鏡で生体分子の構造解析をはじめよう
2021 年 63 巻 2 号 p. 80-88
詳細
2021 年 63 巻 2 号 p. 80-88
About 40 years ago, the basic concept of cryo-electron microscopy was introduced, where biological specimens were kept close to nature state by being embedded in vitreous ice and observed directly with electron microscope. Since then, technology and equipment have improved significantly, making it now possible to determine the atomic coordinates of many biomolecules. Here, we will introduce the latest structural study of biomolecules using single particle cryo-electron microscopy.
