Hosoma (2009) and Joh & Hosoma (2009) presented a new approach for conversation analysis over the speaker-hearer framework in order to expand the previous framework of gesture studies in which generation of speech and gesture in a speaker was mainly discussed (McNeill, 1992; Saito & Kita, 2002). We suggest a guideline for the new conversation analysis to serve as a promising research field that bridges the speech and gesture studies between speaker and hearer. The guideline consisted of two main suggestions in order to reconsider the speaker-hearer framework from a viewpoint of the bilateral character of human nature. The fist is to construct a theory in the new conversation analysis. The recommended task is to examine critical words such as “synchronization”of speech and gesture, and “spontaneous” gesture used in the speaker oriented gesture studies. The second is to consult related research areas such as brain science and sports science in order to share the benefits of using of measurement hardware such as brain imaging. Taken together, conversation and gesture studies will lead to interesting new findings coming from the cooperation among various studies.