2025 Volume 52 Issue 6 Pages 815-820
Recent advances in longevity research have underscored the growing importance of anti-aging medical checkups as a preventive strategy against age-related diseases. Conditions such as cardiovascular disease, cancer, and immune dysfunction are increasingly understood to stem from biological aging processes, including vascular and immunological aging. Anti-aging checkups aim to detect these changes at an early stage and mitigate future disease risk through targeted interventions.
Unlike standard health screenings, anti-aging checkups involve specialized assessments tailored to aging-related biomarkers, with test selection varying by facility. AAD LifeWorks is one such initiative currently in beta development. Its diagnostic framework categorizes results into two domains: current aging status and aging risk factors. Each domain is evaluated using five indicators and visualized via radar charts, enabling identification of individual vulnerabilities. Since aging progresses heterogeneously across systems, the approach emphasizes strengthening weaker domains to promote overall physiological resilience.
To support broader adoption, a web-based platform for AAD LifeWorks was developed beginning in 2022. The system enables secure data upload, automated analysis, and personalized lifestyle guidance. The output includes a 20-page report with pre-filled medical advice, which can be customized by physicians familiar with the patient's context. While the platform enhances usability and clinical integration, future challenges include raising public awareness, embedding the system into routine practice, and ensuring equitable cost distribution for testing.