A case of carcinosarcoma of the maxillary sinus, treated by irradiation and surgery and termnating in death, is presented. The patient is a 69-year-old female with complaints of swelling of the left cheek and bloody rhinorrhea. The x-ray examinations show destruction of bony wall of the sinus. The detailed histopathological examinations (the cytological examination by chymotrypsin lavage, biopsies and microscopic research of the maxillectomized tumor and the recurrent tumors) reveal that the tumor consists of two quite distinct elements-one squamous cell carcinoma and the other osteogenic osteosarcoma.
This lesion shows the following characteristics,(1) Malignant epithelial and stromal elements are simultaneously present.(2) No transitional forms are noted between both elements despite intimate intermixture.(3) No additional tissue elements are present suggestive of a teratoma.(4) Metastasis of osteosarcoma to the bilateral lungs and pleural wall is proved by the autopsy.
Finally this case is diagnosed “true carcinosarcoma” by above mentioned features and the clinical course.