抄録
Behavior of EP modified by anoxia and injection of furosemide was compared on anesthetic and nonanesthetic guinea pigs. The results obtained on both group of guinea pigs were statistically analyzed and no significant differences were observed in all experimental conditions. So the effect of anesthesia on behavior of EP was denied.
The effect of autonomic drugs (adrenalin, noradrenalin. isoproterenol, phenoxy- benzamine, propranolol, acetylcholine, atropine) was observed. In all animals, output of EP decreased ca. 4 my after injection of adrenalin or noradrenalin, and these effets were prevented by preliminary injection of phenoxybenzamine (α-blocking agent) but these were not prevented by propranolol (β-blocking agent).
EP has been considered to be maintained by blood flow of stria vascularis which should be affected by autonomic nervous system. Out of the results obtained by our studies, a-receptor dominant innervation was seemed to exist in the inner ear.
