耳鼻と臨床
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
突発性難聴に対するメチルB12 (メチコバール) 点滴静注の薬効評価
大西 信治郎伊藤 依子
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1986 年 32 巻 4 号 p. 534-546

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Out of 102 sudden deafness cases who were treated at Kanto Teishin Hospital, 57 cases were given intravenous drip of Methyl B12 of 2000μg per day with other drugs as steroid and ATP. Methyl B12 group and non-Methyl B12 group were subdivided into 16 classes according to the two variables that were known to influence recovery from sudden deafness. Initial audiogram was divided into 4 classes and the time since onset was also divided into 4. Wilcoxon two sample tests were conducted on the hearing improvement between MB group and non-MB group in each class at 6 frequencies. MB group showed significantly greater improvement of hearing than non-MB group at 250 and 500Hz (p<0.05).
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