Following a sound stimulation (12KC/S, 120phone) electromyogram was taken in rats sufferi- ng from bilateral otitis medic on the condition that their extremities were fixed.
In the records of E.M.G.in the auricular muscles, extensor and flexor muscles of the poste- rior extremities, the discharge showed an increase in frequency and voltage after a long latent period leading to the development of tonic-clonic convulsion.The result of this electromyogra- phical examination of the each stadium of convulsion was found to correspond to the grossly observed result in the previous experiment.
The present result seems to afford the following interpretation as to the etiology of the audiogenic seizuro.
The development of the audiogenic seizure does not seem attributable to the escaping action of animals but to a diminished buffer mechanism of the middle ear conduction system due to otitis media.The specific sounds cause a diffuse stimulation in the hypolabyrinth.In every neuron of the central nerve system, the impulse is amplified.The system is confused by a conflict between excitation and inhibition, resulting in the incapability of controlling the development of non harmonic impulses.