Auditory brain stem responses were recorded in five patients with cerebello-pontine angle tumor (2 meningionas and 3 acoustic neurinomas). The data were compaired with the results of BSR in animal experiments, and the pssbility of the topographical differential diagnosis for the central lesions by BSR were studied.
The results were as follows.
1) Three cases out of five showed indistinguishable patterns of wave II to wave V.
2) These patterns were considered as the typical BSR in cerebello-pontine angle tumors.
3) In the case of disturbances of cerebello-pontine angle, the decrease of amplitudes and the increase of latencies could be observed in the conponents after wave I.
4) The pattern was coincident with that of destruction of cochlear nucleus in animal studies.