Introduction: Solitary fibrous tumor (SFT) is a rare neoplastic entity which typically originates from the pleura and other serosal tissues, and infrequently in the head and neck region. Case: A 46-year-old male patient complaining of nasal obstruction was referred to us for a tumor in the left nasal cavity. Contrast-enhanced computed tomography showed a heterogeneously enhancing mass. The histopathological findings of this hemorrhagic tumor on the first biopsy were compatible with a nasal polyp; however, a rebiopsy revealed a spindle cell neoplasm which was immunohistochemically positive for CD34 and negative for S-100 protein, which led to the diagnosis of SFT. The tumor was removed by endoscopic medial maxillectomy (EMM), and histopathology of the resected specimen confirmed the preoperative diagnosis. The patient showed no evidence of recurrence until at least five years after the operation. Conclusion: Diagnosis of SFT is confirmed by immunohistochemical study. EMM may be considered as the treatment of choice for maxillary SFT.
