A case of malignant fibrous histiocytoma (MFH) of the maxillary sinus is reported. An 85-year-old man was referred to our OPD clinic because of pain and swelling in the left maxillary region. Radiological investigation showed a tumor of the left maxillary sinus invading the surrounding tissue with bone destruction. Following partial maxillectomy, the patient received radiotherapy, chemotherapy and several additional surgical operations (including Laser surgery). However, local lesions recurred repeatedly. The patient died from general emaciation at his home.
The maxillary sinus is an uncommon site for MFH. We reviewed 24 such cases previously reported. In the treatment of MFH of the maxillary sinus, we cannot hope for much from radiotherapy or chemotherapy. Wide surgical excision is recommended as the primary therapy.