抄録
An orthostatic test (Test 1)and orthostatic test with vasodilator drug (Test 2) were performed to analyze orthostatic dysregulation in vertigo patients. Test 1: Blood pressure and heart rate of 31 control subjects and 64 vertigo patients were serially measured in the prone position for 3 minutes, standing for 10 minutes, and in the prone position for 3 minutes. Test 2: Blood pressure and heart rate of 20 control subjects and 64 vertigo patients after sublingual administration of a nitroglycerin tablet(0.3mg)were serially measured in the prone position for 3 minutes, standing for 10 minutes, and in the prone position for 3 minutes. The profiles of blood pressure and heart rate of normal subjects and vertigo patients were compared by analysis of variance.
In test 1, the positive rate of Schellong test in vertigo patients was similar to that of normal subjects. In addition, the profiles of systolic blood pressure, pulse pressure, and heart rate in vertigo patients were similar to those of normal subjects, except for the difference in systolic blood pressure measured while standing between the two groups. In test 2, profiles of blood pressure in vertigo patients differed from those of normal subjects 1, 8, 9 and 10 minutes after standing. No difference of profiles of pulse pressure or heart rate between the two groups was observed.
It was suggested that orthostatic dysregulation of vertigo patients can be more readily detected by test 2 than by test 1.
