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80 巻, 1 号
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坂倉 康夫1987 年 80 巻 1 号 p. 1-18
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーMucociliary function is the transport of the mucous blanket with trapped foreign materials toward the pharynx. This function is one of the fundamental and irreplaceable defense mechanisms of the respiratory tract against environmental agents. Mucociliary transport can be determined by soluble or insoluble indicators.
Mucociliary transport is governed by three factors;cilia, mucus, and their interaction. A defect of any one of these governing factors or a combination of them causes mucociliary dysfunction. It is, moreover, possible to analyze the causes of mucociliary dysfunction.
Mucociliary dysfunction found in primary ciliary dyskinesia(PCD), including Kartagener's syndrome, is due to abnormal cilia. The dysfunction in the nose in colds lasting for more than 8 weeks is due mainly to decreased numbers of cilia and ciliary beat frequency. Reduced mucociliary transport in the nose of chickens infected by Newcastle disease virus is also due to abnormality of cilia.
High viscoelasticity of mucus could be a cause of mucociliary dysfunction in otitis media with effusion and chronic sinusitis. Decrease of periciliary fluid also could be a cause of dysfunction in these diseases. In chronic sinusitis there is a tethering phenomenon;the mucous blanket is tethered by threads of mucus from secretory cells at multiple points. In this situation, mucociliary stasis occurs with active cilia. Since thetethering phenomenon is found in infection, dehydration, and exposure to SO2, it is probably a universal response to stimulation of the respiratory tract.
Now we can determine mucociliary transport and analyze the cause of mucociliary dysfunction. This knowledge may help to establish the prevention and treatment of mucociliary dysfunction.抄録全体を表示PDF形式でダウンロード (3064K) -
茂木 五郎, 藤吉 達也1987 年 80 巻 1 号 p. 20-21
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーPDF形式でダウンロード (2289K) -
―波形の再現性からの検討―福田 正弘, 庄司 稔, 山岨 達也, 韓 東煕, 深谷 卓, 和田 昌士1987 年 80 巻 1 号 p. 23-32
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーThe diagnostic value of auditory brainstem response (ABR) for the differential diagnosis between acoustic neuromas (AN) and cochlear deafness (CD) was investigated in audiologically paired patients. Wave latencies, interpeak latencies and right and left latency difference of wave V were compared between AN and CD. It was concluded that the right and left latency difference of wave V was useful for the differential diagnosis between AN and CD, and that in almost every patient with AN, the incidence of waves of the same latency decreased inrespective of the degree of the pure tone average.抄録全体を表示PDF形式でダウンロード (4118K) -
―特に聴力の予後について―服部 浩1987 年 80 巻 1 号 p. 33-41
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーOne hundred and fifty one cases of juvenile bilateral sensorineural deafness of unknown etiology were followed up for a period from 5 to 22 years (average 12 years and 2 months) in our department. Hearing (average of 1-4KHz or 1-2KHz) was unchanged (<15dB) in 100 cases (66.2%) fluctuated temporarily (>15dB) in 22 cases (14.6%) and deteriorated permanently in 29 cases (monaurally in 13 cases and bilaterally in 16 cases). The degree of hearing deterioration ranged from 15 to 43dB (average 27dB).
The incidence of hearing deterioration showed no significant difference (α=5%) between aided and unaided ears. The incidence to fluctuation of hearing were significantly higher in deteriorated ears.
The deterioration of hearing occurred in every age groups observed: 6 ears (under10 years), 16 ears (11-15 years), 11 ears (16-19 years) and 12 ears (20-30 years). The discrimination score was high (over 80%) in 37% of the patients but low (0-35%) in 30%.抄録全体を表示PDF形式でダウンロード (973K) -
―10年間の聴力推移を中心として―山際 幹和, 原田 輝彦, 坂倉 康夫, 金 春順1987 年 80 巻 1 号 p. 43-48
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーA 36-year-old female with aortic arch syndrome had sudden bilateral hearing loss and tinnitus without vertigo. Since then, pure-tone audiometry has been repeated for over 10 years. During the period, vertigo was not observed and the hearing disturbances, which were improved temporarily by administration of predonisolone, fluctuated and slowly progressed. Finally, the hearing on the right was completely lost. There were marked similarities among the present patient and 2 patients with sensorineural hearing loss attributed to the aortic arch syndrome, which had been reported by other authors.抄録全体を表示PDF形式でダウンロード (658K) -
長野 三郎, 川野 通夫, 山本 悦生1987 年 80 巻 1 号 p. 49-56
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーThe Tsumori and Inage Developmental Questionnaire Test was performed on 62 hearing impaired infants ranging age from 1 year 1 month to 3 years 4 months. Their averaged hearing level after 2 years of age measured by COR, ABR, and the peep show ranged from 55dB to 105dB.
Average developmental quotient in five aspects such as motor, inquiry and operation, sociability, habits of daily life and language and speech in this test was 102. 7, 90.6, 73.8, 91.1, 58.0 respectively. The profile of hearing impaired infants was more retarded in two of the five aspects; sociability and language and speech.
Hearing impaired infants could not perform 15% of the test items such as “pointing to eyes, ears, mouth, or nose by himself”.
It is concluded that the profile obtained from the Tsumori-test is effective for screening hearing impaired infants from normal infants.抄録全体を表示PDF形式でダウンロード (573K) -
坂田 英治, 伊藤 菜穂子, 伊藤 彰紀, 中沢 宏, 中井川 弘毅, 伊藤 靖郎, 内田 ゆか里, 中野 義博, 寺本 和弘, 馬場 完仁 ...1987 年 80 巻 1 号 p. 57-65
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーWe compared the therapeutic effects of inner ear anesthetic therapy and the middle ear infusion therapy with a steroid solution in patients with Ménière disease who were unresponsive conservative therapy inculuding oral drug therapy.
Inner ear anesthetic therapy was effective in 42 of 47 ears for vertigo, while middle ear infusion was effective in all 21 ears treated.
Although both therapies were ineffective for hearing disturbance, the former therapy was effective for tinnitus in 36 of 57 ears, and the latter in 26 of 42 ears.
For other concomitant symptoms such as full sansation of ear obturation, head heaviness and stiff shoulders, both therapies were considerably effective.
It was concluded that the first choice of therapy for patients with Ménière disease who do not respond to conservative therapies is middle ear steroid infusion at outpatient clinic, and the second choice is inner ear anesthetic therapy, and that both therapies should be considered before resorting to surgical treatment.抄録全体を表示PDF形式でダウンロード (704K) -
朴 茂男, 服部 康夫, 村上 忠也, 太田 文彦, 甲田 嘉彦1987 年 80 巻 1 号 p. 67-75
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーAn orthostatic test (Test 1)and orthostatic test with vasodilator drug (Test 2) were performed to analyze orthostatic dysregulation in vertigo patients. Test 1: Blood pressure and heart rate of 31 control subjects and 64 vertigo patients were serially measured in the prone position for 3 minutes, standing for 10 minutes, and in the prone position for 3 minutes. Test 2: Blood pressure and heart rate of 20 control subjects and 64 vertigo patients after sublingual administration of a nitroglycerin tablet(0.3mg)were serially measured in the prone position for 3 minutes, standing for 10 minutes, and in the prone position for 3 minutes. The profiles of blood pressure and heart rate of normal subjects and vertigo patients were compared by analysis of variance.
In test 1, the positive rate of Schellong test in vertigo patients was similar to that of normal subjects. In addition, the profiles of systolic blood pressure, pulse pressure, and heart rate in vertigo patients were similar to those of normal subjects, except for the difference in systolic blood pressure measured while standing between the two groups. In test 2, profiles of blood pressure in vertigo patients differed from those of normal subjects 1, 8, 9 and 10 minutes after standing. No difference of profiles of pulse pressure or heart rate between the two groups was observed.
It was suggested that orthostatic dysregulation of vertigo patients can be more readily detected by test 2 than by test 1.抄録全体を表示PDF形式でダウンロード (786K) -
松田 常男, 桂 周良, 田村 保憲1987 年 80 巻 1 号 p. 77-81
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーAmong 25 patients with acute otitis media who had otorrhea for more than one week, we studied the sera from 11 patients.
Ten patients were diagnosed as having mycoplasma otitis media on the basis of clinical and laboratory findings, suggesting that the disorder is not rare.抄録全体を表示PDF形式でダウンロード (446K) -
高橋 正紘1987 年 80 巻 1 号 p. 83-91
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーWe reported a 15-year-old male exhibiting middle ear malformation with meatal cholesteatoma who was treated by a transmastoid operation 5 years after a meatoplasty. He showed slight microtia, meatal stenosis of the cartilaginous portion, atresia plate, abnormally located facial nerve, hypoplasia of the tympanum, fusion of the malleus and incus, chorda tympani adjacent to the atresia plate, intact incudo-stapedial joint and marked improvement of mastoid aeration after meatoplasty.
Reconstruction of the opened cavity with an aural cartilage plate (attico-antromastoid reconstruction) was effective not only to obtain normal hearing and ear canal structure, but also to preserve mastoid aeration.抄録全体を表示PDF形式でダウンロード (6391K) -
―近畿大学医学部耳鼻咽喉科における10年間の統計―西本 力, 村田 清高, 田中 久哉, 太田 文彦1987 年 80 巻 1 号 p. 93-100
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーA statistical analysis was performed on 342 patients with facial nerve palsy treated at our clinic between May, 1970 and April, 1980. The incidence of Bell's palsy was 71% (242 patients)and that of Hunt's syndrome 16%. Little difference was detected in the initial palsy scores between Bell's palsy and Hunt's syndrome, but significant differences were after a period of two months. Final recovery was significantly better in those with Bell's palsy. In addition, those receiving early treatment showed better final recovery. Better recovery was obtained in Bell's palsy patients under 40 years of age than in those 40 years or more.抄録全体を表示PDF形式でダウンロード (716K) -
斎藤 武久, 斎藤 等, 佐藤 文彦, 上出 一朗, 吉田 幸夫, 坪川 俊仁1987 年 80 巻 1 号 p. 101-106
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーA five-year-old female visited our hospital because of nasal obstruction and epiphora. The right nasal cavity was occupied by a soft gray tumor. After total resection of the tumor piece by piece, it was considered that the tumor originated from the lateral wall of the right nasal cavity and spread to the right maxillary sinus, ethmoid sinus, and nasal cavity. Histological examination revealed a benign Chondroma. As Chondroma tend to exhibit sarcomatous changes, long-term follow-up is essential.抄録全体を表示PDF形式でダウンロード (3907K) -
内薗 明裕, 昇 卓夫, 伊東 一則, 森山 一郎1987 年 80 巻 1 号 p. 107-113
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーA 19 year-old male with hysterical trismus reported. The patient had various signs such as sudden facial palsy, progressive trismus and spastic type gait disturbance. On the laboratory examinations including X-ray Computed tomography, Electric myogram and Cerebro-spinal fluid analysis, there were no findings suggesting any pathological changes.
The results of psychiatric analysis suggested that these clinical symptoms represented a hysterical reaction.
By Jacobson's progressive relaxation method and symptomatic treatment, these symptoms improved and disappeared completely after three weeks.抄録全体を表示PDF形式でダウンロード (724K) -
田中 佐一良, 桝田 耕, 滝元 徹, 梅田 良三1987 年 80 巻 1 号 p. 115-119
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーRecently, we experienced a case of juvenile nasopharyngeal angiofibroma. The patient was a 15-year-old male who complained of right nasal obstruction. Rhinoscopic examination and CT scan were performed. A vascular tumor derived from the nasopharynx was found to extend through the right ethmoid, sphenoid and maxillary sinuses. Angiography revealed that the main supply of blood to the tumor was from right maxillary artery. Radiation therapy (total 3200 rad) was performed, but it was ineffective. Therefore, superselective catheterization to the base of the tumor and transcatheter arterial embolization were performed. The tumor was then successfully removed by the transpalatine approach. The volume of bleeding during the operation was less than 50ml and there was no post-operative bleeding. Pre-operative embolization with gelfoam was found to be an effective method for reducing blood loss during surgery for this tumor.抄録全体を表示PDF形式でダウンロード (4236K) -
中江 進, 三牧 三郎, 只木 信和1987 年 80 巻 1 号 p. 121-125
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーA 57-year-old man who sustained a contusion on his anterior neck in a traffic accident is reported. Emergency tracheostomy was performed but laryngeal stenosis occurred three weeks later. Two months after that traffic accident, reconstruction of larynx was done. A laryngofissure was made, an adhesive vocal cord was dissected, and the mucous membrane of the nasal septum was transplanted as a free graft to the defective portion of the mucous membrane of the vocal cord. An open wound formed on the anterior neck and a silicone sponge was used as a core mold.
Four months after operation the open wound was closed and the right 8th rib cartilage was used as a framework. He was intubated with a T-tube for six months after closure of the open wound. One year after the traffic mishap the tracheostoma was closed as movement of the vocal cord improved and no misswallowing was seen.抄録全体を表示PDF形式でダウンロード (2533K) -
山本 英一, 折田 洋造, 大塚 信昭, 森田 陸司1987 年 80 巻 1 号 p. 127-131
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーThe usefulness of bone scintigraphy using 99m-Tc-labeled phosphorous compounds was evaluated in 134 of 234 patients with cancers of the head and neck who were treated between June 1975 and March 1985.
The overall positive rate in bone scintigraphy was 49%, but the true-positive rate was 25%. Distant bone metastases were found in 18% of the patients. Fifty-five per cent in the patients with true-positive bone scintigraphy had positive x-ray findings. The most common sites of distant bone metastases in head and neck cancers were the rib and the thoracic vertebrae. The rate of distant metastases increased with the T-classification. No relation was observed between bone scintigraphy and serum alkaline phosphatase activity.
In conclusion, bone scintigraphy with 99m-Tc-diphosphonate was found to be very useful in detecting early bone metastases.抄録全体を表示PDF形式でダウンロード (519K) -
―咽喉頭異常感症との関連―竹内 俊二, 岸本 誠司, 宮下 弘1987 年 80 巻 1 号 p. 133-138
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーThe length of the styloid process was analyzed on 111 (oral) panoramic radiograms. Visualization of the styloid processes on the films was achieved in 178 of the 222 sides. Of these, 66 were taken from patients suffering from abnormal sensation in the throat. The other 112 were the films taken from patients not related to pharyngolaryngeal discomfort and served as controls.
The mean length of the styloid processes among the controls was 22.1mm (S. D.±7.2mm). The mean length among the patients suffering from abnormal sensation was 24.1mm (S. D.±8.0mm) and was significantly longer than that of the controls (p<0.05). Patients, who had abnormal sensation in the epi and/or mesopharynx, and had the identical sensation by palpating the tonsilar fossa, and whose abnormal sensation subsided by blocking the area, were suspected of having styloid syndrome. Those patients had slightly longer styloid processes than that of the entire group of patients with abnormal sensation in the throat.
There was no statistically significant relationship between the length of the stybid process and age, or sex.抄録全体を表示PDF形式でダウンロード (568K) -
暁 清文, Richard L. Goode, Craig Miller1987 年 80 巻 1 号 p. 139-147
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーHearing at the speech frequency range can be improved by modifications of the external and middle ear at the cost of hearing loss at low and/or high frequencies, which are not important for speech recognition. Experiments using the model of the external ear proved that the increase of cavity volume of the external ear changed its resonant peak to lower frequency. Use of a ring in a model of the external ear also showed similar effects. These results showed that hearing could be improved at around 1kHz by 10-20dB. The effects of middle ear modifications were studied with fresh human temporal bones. Stainless steel microspheres placed on the umbo was observed under a microscope with strobe illumination, and the displacement of the umbo was measured using a video measuring system. Blockage of the aditus ad antrum improved the hearing at 2.8kHz by 5.4dB (mean). Decrease of the middle ear cavity volume increased the hearing at 1.4-2.8kHz by 2.2dB (mean).抄録全体を表示PDF形式でダウンロード (862K) -
坂口 幸作, 坂口 文雄, 牛島 勝郎, 坂口 喜清, 吉沢 文子1987 年 80 巻 1 号 p. 149-154
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーTo elucidate the effects of antigen-specific immunotherapy, the number of nasal surface basophilic cells was investigated. Before and 6 months after immunotherapy treatment, specimens were obtained by scratching the mucosal surface of the inferior nasal concha from 28 patients with perennial nasal allergy and the basophilic cells in these specimens were counted.
The number of basophilic cells decreased in 12 patients and increased in 5 patients. The mean number of surface basophilic cells was 948±635 before treatment and 621±573 after treatment, but the difference was not significant.
Furthermore, there was no significant correlation between the change in number of basophilic cells and the change in intensity of symptoms, the number of eosinophils in peripheral blood, eosinophils in nasal smears or serum IgE levels.抄録全体を表示PDF形式でダウンロード (504K) -
佐竹 文介, 清水 龍一, 牧野 総太郎, 松浦 鎮1987 年 80 巻 1 号 p. 155-161
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーA new antracycline anti-tumor agent, (2''R)-4'-0-tetrahydropyranyl adriamycin (THP), was used in the treatment of 15 cases of head and neck malignant tumors, and the primary effects and side effects were examined in 15 cases.
The histopathological daiagnosis was squamous cell carcinoma in 13 cases, malignant melanoma in 1 case and fibrosarcoma occuring after treatment of tongue cancer in 1 case.
The primary lesion was nasopharyngeal carcinoma in 1 case, mesopharyngeal carcinoma in 2 cases, hypopharyngeal carcinoma in 1 case, laryngeal cancer in 2 cases, tongue cancer in 4 cases, gum cancer in 2 cases, maxillary cancer in 1 case, malignant melanoma of the maxillary sinus in 1 case and fibrosarcoma of the tongue in 1 case. Three patients had no prior treatment and 12 had recurrences. THP was administered by intravenous infusion in 7 patients, by local intraarterial infusion in 7 and both intravenous and intraarterial routes in one. The therapeutic effect of THP was rated as PR in 5 cases, MR in 2 cases, NC in 7 cases and PD in one case. The overall response rate was 33.3%, but in the intraarterial infusion group it was 71.4%. These results indicate that intraarterial infusion of THP is more effective than intravenous infusion. No severe side effects of THP were observed in the 15 cases in this study, but there was a slight decrease in the W. B. C. count in 12 cases.
THP apPears to be an excellent antitumor agent for neo-adljuvant chemotherapy of head and neck advanced cancers because of itsnegligible sideeffects.抄録全体を表示PDF形式でダウンロード (2082K) -
伊東 眞人, 坂田 義治, 阪上 雅史, 宮口 衛, 久保 武, 酒井 俊一1987 年 80 巻 1 号 p. 163-167
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーThe therapeutic effects of Varidase in 33 patients with abnormal sensation in the throat was evaluated. The patients were given 6 tablets of Varidase daily for more than 2 weeks. The abnormal sensation disappeared in 10 patients and partially subsided in 14 patients. Fifteen had tonsillitis, which was considered to be responsible for these sensations. These patients were more nervous and less responsive to the drug than the other patients.抄録全体を表示PDF形式でダウンロード (428K) -
山本 悦生1987 年 80 巻 1 号 p. 168-169
発行日: 1987/01/01
公開日: 2011/11/04
ジャーナル フリーPDF形式でダウンロード (241K)
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