Abstract
The Japan Flavor & Fragrance Materials Association (JFFMA) has conducted poundage surveys of flavoring substances used in
Japan in 2001, 2005, 2010 and 2015. The number of flavoring substances used in Japan was the maximum in 2001 and has been
decreasing thereafter. The reason for this decline is thought to be the discontinuation of use of flavoring substances that were used
only in Japan in response to the globalization of flavor regulations and changes in consumer preferences, resulting in increased
unification with internationally accepted flavoring items. The estimated daily intake of flavoring substances was calculated by the
MSDI method, and the number of flavoring substances for each range of estimated intake was compared. It is generally said that “the
characteristics of flavor ingredients are small amounts and multi-components” and this was verified by the four poundage surveys in
Japan. In order to provide up-to-date exposure data for scientific safety assessment, it is desirable that poundage surveys of flavoring
substances are conducted regularly.
