Abstract
Objective: This article discusses the influence caused by the leaders of the Fushimiya Ichibei Company (later, Ono Pharmaceutical CO., LTD.) during the Meiji and Taisho Eras.
Method : The paper surveys company history, memoirs, and industry history.
Results : Fushimiya Ichibei (later, Ono Ichibei) performed important negotiations against governmental organizations about the rules of the pharmaceutical industry. These contributed to establishing the
foundations for medicine dealers who tended to adapt to new systems.
Conclusion : Three leaders of the company had preserved their business and contributed to the progress of Doshomachi during the turbulent times. Their activities also became the basis of the innovation later made by Yuzo Ono.
