糸状菌ゲノム解析への招待⑴

抄録

This article reviews basic concepts, current status, and the potential applications of genomics on mycology, along with providing brief introductions of currently available technologies for experimental and bioinformatics approaches. The development of methodologies of bioinformatics and functional genomics, such as transcriptome, proteome, and metabolome analyses, enables the genome-wide study of various genetic phenomena related to filamentous fungal cells. An increase in the speed of genome sequencing would increase the number of genera that can be studied by comparative genomic analysis. Data obtained by functional and comparative genomic analyses may explain phenomena associated with vast numbers of genes. Genomics can provide an effective functional analysis of vast numbers of genes with unknown functions. The advent of next-generation sequencers will facilitate fast and cost-effective genome sequencing leading to the deciphering of more genome sequences, thereby enhancing the effectiveness of functional and comparative genomics. In the near future, genomic analysis will be incorporated into various fields of mycology. This review is an introduction to the current status of potentially useful technologies and strategies that are available for genomic and proteomic applications in mycology.